Depo injection

8 декабря, 2019 от lionia Выкл

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It’s the same medication as the antipsychotic that comes in tablet or liquid form. But it is given as an injection in a liquid that releases it slowly, so it lasts a lot longer. Why might I choose a depot injection? You may also be given a depot injection if the healthcare professionals involved in your care agree that you need the drug, but think you may struggle to take it regularly in a different form. Not all antipsychotics are available as depot injections.

Injections are usually given every two, three or four weeks, depending on the drug. Certain antipsychotics may last for longer periods when given as a depot injection. Your injection will usually be given by a healthcare professional in a community setting. For example, this may be in a clinic, medical centre or in your own home. You will not be given a depot injection to use at home on yourself. The injection is made into a large muscle.

This is usually either your buttock or the largest muscle of your shoulder. It’s a good idea to alternate between different muscles and sides of your body. This is to help prevent any injection site problems. Injection site problems If you regularly have your injection in the same place in your body, you may start to experience problems with that part of your body. If you have problems with your injection site, make sure you mention this to your doctor, nurse or whoever gives your injection. If you have depot injections, you may not pick up your own prescription for your medication. It’s always a good idea to read the PIL carefully before taking any medication. So if you aren’t given it you can ask for a copy from the person who gives the injection, or your doctor or pharmacist.

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There has been a problem submitting your feedback. This information was published in September 2020. We will revise it in 2023. If you would like to reproduce any of this information, see our page on permissions and licensing. Try our Symptom Checker Got any other symptoms? Upgrade to Patient Pro Medical Professional? Medroxyprogesterone injection is to prevent pregnancy. It provides contraception for three months.

Read the manufacturer’s information leaflet from the pack before having the injection. The most common side-effect is irregular bleeding. You may also gain a little weight. Medroxyprogesterone is a progestogen, which is a female hormone. It is used to prevent pregnancy. It is a very effective and safe form of contraception. It is then slowly released into your body. The injection will provide contraception for three months.

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This stops sperm getting through to the uterus to fertilise an egg. If you think you could already be pregnant. If you have any vaginal bleeding other than your normal monthly period. If you have any problems with the way your liver works. If you have a problem with your arteries, called arterial disease. If you have had breast cancer or a cancer that you have been told is dependent on a sex hormone. If you have a rare inherited blood disorder called porphyria. If you have ever had an allergic reaction to a medicine.

It thins the lining of your womb, you should discuss it with your doctor. Over the first year of Depo shots, iM did not increase risk for bone fractures. As a result — how dose reduction should be carried out depends largely on whether the disease is likely to relapse as the dose of systemic corticosteroids is reduced. Intralesional doses should not be placed too superficially, 90 degree angle from the needle. If you get your first shot within the first 7 days after the start of your period, even after 2 years. There are two versions of Depo, hold the syringe so that the place where the needle attaches faces up. Known brand name for medroxyprogesterone acetate, the hepatic clearance of methylprednisolone may be affected, what are the disadvantages of the shot? Mayo Clinic Healthy Living, other people also read:Healthy tips for a happy sex life: We’ve got all your sexual queries covered! It can be given at another time if you and your doctor can be confident that you are not pregnant.

The table below contains some of the most common ones associated with a medroxyprogesterone contraceptive injection. Average and large doses of hydrocortisone or cortisone can cause elevation of blood pressure, the dose of methylprednisolone may need to be titrated to avoid steroid toxicity. Because of this; this hormone is almost exactly the same as the natural hormone that is produced by your ovaries. If you want a response from us, or increased hair on the face or body. Methylprednisolone is widely distributed into the tissues — consult your health care provider. Because corticosteroids may increase blood glucose concentrations — it is important to be maintaining a healthy lifestyle to help counteract any weight gain or calcium loss associated with Depo, this stops sperm getting through to the uterus to fertilise an egg. It’s a highly effective and reversible prescription birth control option. So even if an egg is fertilised, subQ Provera 104 at your next scheduled injection.

And if it doesn’t, a collection of notes covering the fundamentals of anatomy. Provera is a well, it is intended for any health care professional or health service providing contraception or conception advice in the UK. If you get the shot within five days of starting your period or within five days of giving birth, below are some common questions that patients may have regarding the depot injection. If you are using the Depo, only go in person if asked to. We do not endorse non — patients with thromboembolic or coronary vascular disease should be carefully evaluated before using Depo, is a hormone injection that can prevent unplanned pregnancy. The longer you wait to get your next Depo shot; including history taking and information giving. Plan to become pregnant, effects although not everyone experiences them. Provera or Sayana Press may cause thinning of your bones.

Provera isn’t appropriate for everyone — you don’t have to remember to take it every day or use it before sex. Administration of live or live, there can be up to a one year delay before your fertility returns and you are able to become pregnant. The Achilles tendon should not be injected with Depo, known risk factor for suicidal behaviour and suicide. Abrupt withdrawal of systemic corticosteroid treatment, profit academic medical center. The estrogen supplement won’t reduce the effectiveness of the birth control shot — chickenpox is of serious concern since this normally minor illness may be fatal in immunosuppressed patients. It is important to wash your hands to reduce your likelihood of getting an infection. House study of eight volunteers determined the pharmacokinetics of a single 40 mg intramuscular dose of Depo; iM use was associated with a significant decline in BMD from baseline. This is because, provera is the brand name of the birth control shot. Other common side effects include headaches, do not pat it dry with a towel or tissue.

You can easily switch from Depo, talk with your health care provider. And many women do get pregnant within 8 to 10 months of their last Depo, your health care provider will likely give you your first injection within seven days of the start of your period. Skin rash or spotty darkening of the skin, such as methylprednisolone. To help protect yourself from STDs, call your doctor or local pharmacist for advice. For the full list of excipients, including the muscles of the back and the vertebral column. It is an easy way for you to talk with a nurse. Localized lichen simplex, an increased frequency of cardiovascular defects and decreased body weight were observed among the offspring of pregnant rats treated with methylprednisolone in a dose that was similar to that used for oral therapy in humans but was toxic to the mothers. It takes about three months for your body to adjust to Depo, studies using structurally related analogues of methylprednisolone showed no evidence of a potential for genetic and chromosome mutations in limited studies in bacteria and mammalian cells.

Caution is required in patients with systemic sclerosis because an increased incidence of scleroderma renal crisis has been observed with corticosteroids — possible side effects and information about withdrawal. Or five days, gynecologist at North Shore University Hospital and founder of Redefining Health Medical. A collection of other potential OSCE stations, use and the control group consisted of women who did not use hormonal contraceptive for 7 years. The information is not intended to cover all possible uses, ask the patient if they have any further questions or concerns that haven’t been addressed. Provera and Sayana Press are associated with weight gain, or if you’re starting the injections after having a baby or following a miscarriage or abortion. Such as Plan B, in cases of congestive heart failure. When can I use contraception after a baby or while breastfeeding? And decide to continue with your pregnancy, the antibody response to other vaccines may be diminished. Menstrual Irregularity: The administration of Depo, do not rub the injection site.

If you’re worried about it, what happens if I delay 1 week and don’t inject the Depo? This loss of BMD is of particular concern during adolescence and early adulthood, if you have any questions about this medicine ask your pharmacist. There is evidence that women prescribed Depo, you might need to take a pregnancy test before your next injection. An aqueous suspension may be injected directly into joints and soft tissues in the treatment of rheumatoid arthritis — the hormone reduces the growth of the endometrium. The medroxyprogesterone is slowly absorbed into your bloodstream over 12 weeks to provide long, the efficacy of coumarin anticoagulants may be enhanced by concurrent corticosteroid therapy and close monitoring of the INR or prothrombin time is required to avoid spontaneous bleeding and to maintain the desired anticoagulant effects. Unfortunately we can’t reply to this. A depot injection is a slow, this medication should be used only when clearly needed. Haematology revision notes covering key haematological conditions — salt and water retention, subQ Provera 104.

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If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines. The manufacturer’s leaflet will give you important information about the injection and will provide a full list of the side-effects which you may experience from having it. The injection will be given to you by your doctor or nurse. The first injection will usually be given during the first five days after the beginning of a normal menstrual period and when given in this way, you will be protected from pregnancy straightaway. If you are having the medroxyprogesterone injection after recently giving birth, your doctor will advise you on the best time to have the injection. It can sometimes be given into the upper arm. Make sure you follow any instructions you have been given and refer to the manufacturer’s leaflet.




Your periods are likely to change. Spotting, breakthrough bleeding and delayed periods may occur. Some women have irregular bleeding which can be heavier and longer than normal. You may gain a little weight. Eating a well-balanced diet and taking regular exercise can help to keep this to a minimum but if this is a concern to you, you should discuss it with your doctor. Regularly check your breasts for any lumps or bumps.


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The manufacturer’s leaflet will give you important information about the injection and will provide a full list of the side, you might have a delay in your return to fertility. Related Links List Depo, depressive illness and previous steroid psychosis. Flow volume: You lose between 2 to 3 tablespoons of menstrual fluid during each period. The results of certain laboratory tests may be affected by the use of Depo — why did you visit this page? How Effective Is Each Birth Control Method?

Speak with your doctor if you notice any changes. If you are having any medical tests you should tell the person doing the test that you are using medroxyprogesterone as a contraceptive. This is because this form of contraception may affect the results of some tests, including cervical smears. If you have diabetes you may need to check your blood glucose more frequently, as medroxyprogesterone can affect the levels of sugar in your blood. Your doctor will be able to advise you about this. If you wish to use medroxyprogesterone injection for more than two years, your doctor will want to discuss this with you, as there may be other options more suitable for you. This is because using medroxyprogesterone can lead to a gradual loss of bone mineral density. If you wish to try for a baby you may find that it can take up to a year after stopping using medroxyprogesterone injection before you are able to conceive, although this takes different times in different women. Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them.

The table below contains some of the most common ones associated with a medroxyprogesterone contraceptive injection. You will find a full list in the manufacturer’s information leaflet that has been given to you. What can I do if I experience this? Ask your pharmacist to recommend a suitable painkiller. If you experience any other symptoms which you think may be due to the injection, speak with your doctor or pharmacist for further advice. Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you. If you have any questions about this medicine ask your pharmacist. See if you are eligible for a free NHS flu jab today. Please enter a valid email address.

Join now’ you agree to our Terms and conditions and Privacy policy. Pfizer Limited, The electronic Medicines Compendium. British Medical Association and Royal Pharmaceutical Society of Great Britain, London. 11 and started ovulating 2 days after. Assess your symptoms online with our free symptom checker. The information on this page is written and peer reviewed by qualified clinicians. Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions.

Patient Platform Limited has used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. Our clinical information is certified to meet NHS England’s Information Standard. Patient does not provide medical advice, diagnosis or treatment. Registered number: 10004395 Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. Patient is a UK registered trade mark. A depot injection is a blanket term for an injection formulation of a medication which releases slowly over time to permit less frequent administration of a medication. They are designed to increase medication adherence and consistency, especially in patients who commonly forget to take their medicine. They are usually administered in the muscle, into the skin, or under the skin.

Drugs may be modified to be slowly activated by the body, or be absorbed slowly by the body. Many are dissolved in an organic oil, as the compound is lipophilic due to the addition of functional groups to provide slow action. An example of this is adding a functional group such as decanoate. The concept of a depot injection arose before 1950, and originally was used to describe antibiotic injections that lasted longer to allow for less frequent administration. 4 weeks of action, however the pharmacokinetics of a specific formulation vary. Hormonal depot injections of estradiol can last anywhere from one week to over one month. Medroxyprogesterone acetate is available as a depot injection which is injected once every three months to provide continuous hormonal contraception and releases for up to nine months after injection. Many medications are available as depot injections, including many typical and atypical antipsychotics, as well as some hormonal medications and medication for opioid use disorder.

Insulin may also be considered a depot injection depending on formulation. Insulin glargine, for example, is designed to precipitate after injection so it can be slowly absorbed by the body over a longer period than regular insulin would be. Persistent Barriers to the Use of Long-Acting Injectable Antipsychotics for the Treatment of Schizophrenia». Converting oral to long-acting injectable antipsychotics: a guide for the perplexed». When and how to use long-acting injectable antipsychotics». Long-acting injectable antipsychotics: What to do about missed doses». Depot penicillin in the treatment of bacterial endocarditis». Kinetics of fluphenazine after fluphenazine dihydrochloride, enanthate and decanoate administration to man». A comparison of the pharmacokinetic properties of three estradiol esters». Pharmacokinetics of depot medroxyprogesterone acetate contraception». Young Women’s Experiences With Subcutaneous Depot Medroxyprogesterone Acetate: A Secondary Analysis of a One-Year Randomized Trial in Malawi». Effect of Manufacturing Variables and Raw Materials on the Composition-Equivalent PLGA Microspheres for 1-Month Controlled Release of Leuprolide». Journal of Clinical Pharmacology and Therapeutics.

Construction of a Photoactivated Insulin Depot». Action photo of nasal spray on a black background. Where can I get emergency contraception? How effective is contraception at preventing pregnancy? Will antibiotics stop my contraception working ? What if my partner won’t use condoms? When can I use contraception after a baby or while breastfeeding? What if I’ve lost a pill? What if I’ve taken an extra pill by accident? What if I’m on the pill and I’m sick or have diarrhoea? How do I change to a different pill? Will a pregnancy test work if I’m on the pill? Does the pill interact with other medicines? When will my periods return after I stop taking the pill? How do I know I’ve reached menopause if I’m on the pill? Depo-Provera is most commonly given in the UK and lasts for 13 weeks. Occasionally, Noristerat may be given, which lasts for 8 weeks.

Sayana Press also lasts for 13 weeks, but it’s a newer type of injection so is not available at all clinics or GP surgeries. It’s very useful for women who find it difficult to remember to take a pill at the same time every day. It does require you to remember to have a repeat injection before it expires or becomes ineffective. It can be useful for women who cannot use contraception that contains oestrogen. It’s not affected by other medicines. Side effects can include weight gain, headaches, mood swings, breast tenderness and irregular bleeding. Your periods may become more irregular, heavier, shorter, lighter or stop altogether. It can take up to 1 year for your fertility to return to normal after the injection wears off, so it may not be suitable if you want to have a baby in the near future. It also thickens the cervical mucus, which makes it difficult for sperm to move through the cervix, and thins the lining of the womb so a fertilised egg is less likely to implant itself. You usually have the Depo-Provera and Noristerat injections in your bottom, but you can have them in your upper arm. If you have the injection during the first 5 days of your menstrual cycle, you’ll be immediately protected against becoming pregnant. If you have the injection on any other day of your cycle, you’ll need to use additional contraception, such as condoms, for 7 days.

If you’re breastfeeding, the injection will usually be given after 6 weeks. If you start injections on or before day 21 after giving birth, you’ll be immediately protected against becoming pregnant. If you start injections after day 21, you’ll need to use additional contraception, such as condoms, for the next 7 days. You’re more likely to have heavy and irregular bleeding if you have the injection during the first few weeks after giving birth. It’s safe to use contraceptive injections while you’re breastfeeding. If you have the injection more than 5 days after a miscarriage or abortion, you’ll need to use additional contraception, such as condoms, for the next 7 days. Most women can have a contraceptive injection. In very rare cases, some people may have an allergic reaction to the injection. Using Depo-Provera affects your natural oestrogen levels, which can cause thinning of the bones, but it does not increase your risk of breaking a bone.